Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole
R. J. Kukurudz, M. Chapel, Q. Wonitowy, A.-R. A. Bukari, B. Sidney, R. Sierhuis, A. Gerstein
This study evolves C. albicans strains in posaconazole, finding common drug tolerance and aneuploidy, with cross-tolerance to other azoles.
bioRxiv · Jan 6, 2022Evolutionary Biology