Distinct molecular targets for macrocyclic lactone and isoxazoline insecticides in the human louse: new prospects for the treatment of pediculosis
C. L. Charvet, N. Lamassiaude, B. Toubate, C. Neveu, P. Charnet, C. Dupuy, F. Debierre-Grockiego, I. Dimier-Poisson
This study identifies the molecular targets of ivermectin and lotilaner in human lice, showing ivermectin acts on glutamate channels and lotilaner on GABA channels.
bioRxiv · Aug 6, 2020Pharmacology & Toxicology