Functional Test of a Naturally Occurred Tumor Modifier Gene Provides Insights to Melanoma Development
M. Garcia-Olazabal, M. C. Adolfi, B. Wilde, A. Hufnagel, R. Paudel, Y. Lu, S. Meierjohann, G. G. Rosenthal, M. Schartl
The paper tests the function of adgre5 alleles in melanoma development using Xiphophorus hybrids and finds that the X. birchmanni allele suppresses melanoma while the X. malinche allele does not.
bioRxiv · Nov 14, 2023Cancer Biology