PTPN14 Degradation by High-Risk Human Papillomavirus E7 Limits Keratinocyte Differentiation and Contributes to HPV-Mediated Oncogenesis
J. Hatterschide, A. E. Bohidar, M. Grace, T. J. Nulton, B. Windle, I. M. Morgan, K. Munger, E. A. White
This study shows that high-risk HPV E7 degrades PTPN14, impairing keratinocyte differentiation and contributing to oncogenesis independent of RB1 inactivation.
bioRxiv · Nov 16, 2018Microbiology