Maternal Western-style Diet Promotes Immune Tolerance and Liver Sinusoidal Endothelial Cell Dysfunction in Nonhuman Primate Juvenile Offspring Liver
Michael J. Nash, Benjamin N. Nelson, Molly Mae McGuckin, Rachel C. Janssen, Kenneth L Jones, Saif I. Al‐Juboori, Evgenia Dobrinskikh, Paul Kievit, Kjersti Marie Aagaard, Carrie E. McCurdy, MAUREEN A. GANNON, Stephanie R. Wesolowski, Jacob E. Friedman
This study shows that maternal Western-style diet during pregnancy and lactation alters immune and endothelial cell function in juvenile nonhuman primate offspring livers, promoting immune tolerance and fibrosis.
bioRxiv · Jan 7, 2026 · PreprintImmunology