XRN1 couples RNA granule remodelling to global mRNA decay triggered by the activity of a viral endoribonuclease
Gill Elliott, Alistair Tweedie, Carla S Möller-Levet, Benjamin Towler
The paper investigates how XRN1 links RNA granule remodeling to global mRNA decay triggered by the viral endoribonuclease vhs, revealing a sequential model of translational arrest and degradation.
bioRxiv · Nov 4, 2026 · PreprintCell Biology