Characterizing the molecular regulation of inhibitory immune checkpoints with multi-modal single-cell screens
Efthymia Papalexi, Eleni P. Mimitou, Andrew Butler, Samantha D. Foster, Bernadette Bracken, William M. Mauck, Hans‐Hermann Wessels, Yuhan Hao, Bertrand Z. Yeung, Peter Smibert, Rahul Satija
The paper uses multi-modal single-cell screens to identify regulators of PD-L1 expression and develops a computational framework to improve analysis of perturbation data.
Nature Genetics · Mar 1, 2021Peer-reviewedGenomics