Author

Bernadette Marrero

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriana A. de JesusiD· 1 shared Aleksandra Nita‐LazariD· 1 shared Andre T. RastegariD· 1 shared Angélique BiancottoiD· 1 shared Anna Huttenlocher AiD· 1 shared Cameron Manes· 1 shared Carmelo Carmona‐RiveraiD· 1 shared Christopher T. BoughteriD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adriana A. de JesusORCID

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Author profile →

2 papers

Recent·Most cited

Macrophages tune responses to pathogen dynamics through TLR4 stimulation memory and by licensing susceptibility to IL-10

Hannes Bongartz, Christopher T. Boughter, Bernadette Marrero, Thorsten Prüstel, Clinton J. Bradfield, Julia L. Gross, Rachel A. Gottschalk, Aleksandra Nita‐Lazar, Iain D. C. Fraser, Martin Meier‐Schellersheim

The paper shows macrophages use TLR4 memory and IL-10 susceptibility gating to adjust inflammation based on pathogen dynamics.

bioRxiv · Mar 28, 2024 · PreprintImmunology

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome

Adriana A. de Jesus, Guibin Chen, Dan Yang, Tomáš Brdička, Natasha M. Ruth, David A. Bennin, Dita Cebecauerová, Hana Malcová, Helen Freeman, Neil Martin, Karel Švojgr, Murray H. Passo, Farzana Bhuyan, Sara Alehashemi, Andre T. Rastegar, , Raphaela T. Goldbach‐Mansky

This study identifies de novo LYN variants causing constitutive Lyn kinase activation, leading to neutrophilic vasculitis and liver fibrosis, and shows therapeutic response to Src kinase inhibitors.

Nature Communications · Mar 17, 2023Peer-reviewedGenetic & Genomic Medicine