Molecular response to the non-lytic peptide bac7 (1-35) triggers disruption of Klebsiella pneumoniae biofilm
Robert L. Beckman, Berta Martinez, Flor Z. Santiago, Gabriela N. Echeverria, Bruno V. Pinheiro, Marcelo D. T. Torres, Logan Suits, Shantal Garcia, Paeton L. Wantuch, César de la Fuente‐Núñez, Prahathees J. Eswara, David A. Rosen, Renee M. Fleeman
This paper investigates the anti-biofilm mechanism of bac7 (1-35) against Klebsiella pneumoniae, showing it disrupts bacterial membranes and ribosomal function, leading to biofilm collapse and reduced dissemination.
PLoS Pathogens · Dec 1, 2025Peer-reviewedMicrobiology