SPIN: A Scalable Bioinformatics Pipeline for Screening Pathogenicity Related Host-Pathogen Protein INteractions Using AlphaFold3
Zhenghong Bao, Harsh Khanna, Bhuvan Dhand, Wardatou Boukari, Trishna Tiwari, Mousami Poudel, Carlos D. Messina, Mukesh Jain, José C. Huguet‐Tapia, Rosemary Loria
SPIN uses AlphaFold3 to predict host-pathogen protein interactions in plant pathogens, improving prediction reliability with a multi-metric scoring framework.
bioRxiv · Apr 23, 2026 · PreprintGenomics