Using imputed genotype data in the joint score tests for genetic association and gene-environment interactions in case-control studies
Minsun Song, Bill Wheeler, Neil Caporaso, Maria Teressa Landi, Nilanjan Chatterjee
This paper develops methods for analyzing imputed SNPs in case-control studies of gene-environment interactions, showing they maintain type-I error rates and improve efficiency.
bioRxiv · Jul 4, 2016Genetics