Author

Binze Shi

Northwestern Polytechnical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ashley P. NgiD· 1 shared Fuyi LiiD· 1 shared Jie LiuiD· 1 shared Luke IsbeliD· 1 shared Michael J. RoyiD· 1 shared Tong PaniD· 1 shared Xuequn ShangiD· 1 shared Yi Hao· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Ashley P. NgORCID

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1 paper

Recent·Most cited

DesignMaster: A Multi-Conditional Diffusion Framework for Rational PROTAC Design

Binze Shi, Yi Hao, Jie Liu, Tong Pan, Luke Isbel, Michael J. Roy, Ashley P. Ng, Xuequn Shang, Fuyi Li

DesignMaster improves PROTAC design by incorporating linker length and physicochemical constraints through a diffusion framework, achieving better validity and recovery than existing methods.

Bioinformatics · Sep 23, 2026Peer-reviewedBioinformatics