HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous recombination repair
Ramona Haji‐Seyed‐Javadi, Allyson E. Koyen, Sandip Kumar Rath, B Wu, Matthew Z. Madden, Yingzi Hou, Priya Kapoor-Vazirani, Roshika Roshika, Meili Aiello, Nho Cong Luong, Wei-Che Tseng, Fatmata Sesay, J G Kim, Tony Tan, Seohyun Kim, , David S. Yu
This study identifies HELZ as an RNA-DNA helicase that resolves R loops to support homologous recombination repair and genomic stability.
Nature Communications · Jul 23, 2026Peer-reviewedMolecular Biology