Author

Briar Jochim

Fred Hutch Cancer Center

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Genetics· 1

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

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Irini TopalidouiD· 1 shared Nicolas J. LehrbachiD· 1 shared

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2025-2025 · peak 1/yr

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Irini TopalidouORCID

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1 paper

Recent·Most cited

Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2.

Briar Jochim, Irini Topalidou, Nicolas J. Lehrbach

The paper shows that sequence editing of SKN-1A/Nrf1 regulates its transcriptomic output, revealing distinct and overlapping functions with SKN-1C/Nrf2 in stress responses.

PLoS Genetics · Jul 7, 2025Peer-reviewedGenetics