Author

Britta Werthmann

Otto-von-Guericke-Universität Magdeburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Wolfgang MarwaniD· 3 shared Markus HaasiD· 2 shared Viktoria Rätzel· 2 shared Jan Strube· 1 shared Pauline Marquardt· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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3 shared papersSystems Biology

Wolfgang MarwanORCID

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3 papers

Recent·Most cited

Quantifying 35 transcripts in a single tube: Model-based calibration of the GeXP RT-PCR assay

Pauline Marquardt, Britta Werthmann, Viktoria Rätzel, Markus Haas, Wolfgang Marwan

The paper develops a kinetic model and data processing workflow to calibrate the GeXP RT-PCR assay for precise transcript quantification in Physarum polycephalum.

BMC Biotechnology · Apr 14, 2021Peer-reviewedSystems Biology

Disentangling a Complex Response in Cell Reprogramming and Probing the Waddington Landscape by Automatic Construction of Petri Nets

Viktoria Rätzel, Britta Werthmann, Markus Haas, Jan Strube, Wolfgang Marwan

The paper uses Petri nets to analyze gene expression trajectories in Physarum polycephalum, revealing developmental routes, metastable states, and molecular signatures in cell reprogramming.

Biosystems · Jan 7, 2020Peer-reviewedSystems Biology

Developmental switching in Physarum polycephalum: Petri net analysis of single cell trajectories of gene expression indicates responsiveness and genetic plasticity of the Waddington quasipotential landscape

Britta Werthmann, Wolfgang Marwan

The paper analyzes gene expression trajectories in Physarum polycephalum using Petri nets to model developmental switching and genetic plasticity in response to light stimuli.

Journal of Physics D Applied Physics · Sep 21, 2017Peer-reviewedSystems Biology