Deep-learning-driven tumor microenvironment profiling improves immunotherapy response prediction
Ruohan Wang, Brooks A. Benard, Ilayda Ilerten, Sabrina Zdravkovic, Reem Al-Humadi, Sahar Nasr, Brooke Howitt, Andrew J. Gentles
EcoNet improves immunotherapy response prediction by modeling tumor microenvironment signaling networks, outperforming existing methods in AUC and stratifying ccRCC patients by clinical outcome.
bioRxiv · Oct 13, 2026 · PreprintBioinformatics