Atomic Layering Thermostable Antigen and Adjuvant (ALTA(R)) platform provides unique antigen delivery system through controlled release to improve immune response to vaccination
Keith A. Strand, Heather D’Angelo, Ashley M Gerwing, Isabella R. Walters, Emma M. Snyder, Alyssa M Ritter, Emily M. Hite, Yalini H. Wijesundara, Annie B Caplan, Daria Leonidovna Ivanova, Isabella Allen, Yu Han, Lorena R. Antúnez, Antu Dey, Bryan L. Steadman, Sky W. Brubaker
This paper demonstrates that ALTA(R) vaccine particles provide sustained antigen release, improving immune response to single-shot vaccination compared to liquid regimens.
bioRxiv · Jan 5, 2026 · PreprintImmunology