Author

Bryan Lo

Ontario Institute for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam D. EwingiD· 1 shared Adriana SalcedoiD· 1 shared Alex Buchanan· 1 shared Ali KarimnezhadiD· 1 shared Amit G. DeshwariD· 1 shared Catalina V. AngheliD· 1 shared Christine P’ng· 1 shared Christopher M. LalansinghiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Adam D. EwingORCID

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2 papers

Recent·Most cited

Accuracy and Reproducibility of Somatic Point Mutation Calling in Clinical-Type Targeted Sequencing Data

Ali Karimnezhad, Gareth Palidwor, Kednapa Thavorn, David J. Stewart, Pearl A. Campbell, Bryan Lo, Theodore J. Perkins

This study evaluates somatic mutation calling accuracy and reproducibility in clinical-type targeted sequencing data using cell line samples and multiple variant callers.

BMC Medical Genomics · Oct 15, 2020Peer-reviewedBioinformatics

Creating Standards for Evaluating Tumour Subclonal Reconstruction

DREAM SMC-Het Participants, Adriana Salcedo, Maxime Tarabichi, Shadrielle M. G. Espiritu, Amit G. Deshwar, Matei David, Nathan M. Wilson, Stefan C. Dentro, Jeff A. Wintersinger, Lydia Liu, Minjeong Ko, Srinivasan Sivanandan, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, , Paul Christopher Boutros

This study develops quantitative metrics and simulated datasets to evaluate subclonal reconstruction methods in tumours.

Nature Biotechnology · Jan 1, 2020Peer-reviewedBioinformatics