Biomarker Variability Limits Individualized Amyloid Time Estimation in Alzheimer Disease
Julie K. Wisch, Ziqiao Jiao, Peter R Millar, Nicole Sarah McKay, Aleksandra Beric, Wenjing Lin, Bryce Baker, Jennifer Stauber, Sam Rose Preminger, Mathias Jucker, Nicolas R. Barthélemy, Jasmeer P. Chhatwal, Natalie Sarah Ryan, Suzanne E. Schindler, John C. Morris, , Laura Ibáñez
This study evaluates how biomarker variability affects individualized amyloid time estimation in Alzheimer's disease, finding that inter-individual variability is the main source of error.
bioRxiv · Jul 13, 2026 · PreprintBioinformatics