The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis
Jannik Ruwisch, Aurélie Cazes, Lena Maureen Leiber, Raphaël Borie, Lavinia Neubert, C Leonard, Vincent de Montpréville, Adam Szmul, Farah Moussa, Stijn E. Verleden, Svenja Gaedcke, Jan Hegermann, Jan Fuge, Matthias Ballmaier, Jan C. Kamp, , Jonas C. Schupp
This paper presents the first single-nucleus RNA sequencing atlas of pleuroparenchymal fibroelastosis, identifying novel cell states and their spatial organization in lung fibrosis.
Science Advances · May 8, 2026Peer-reviewedCell Biology