MEK1/2 in Rhabdomyosarcoma
K. A. Crawford, M. M. Cleary, C. A. Ricker, M. N. Svalina, J. F. Shern, H.-I. H. Chen, N. E. Berlow, C. A. Keller, G. A. Li
This study evaluates the combination of MEK inhibitor cobimetinib and chemotherapy in rhabdomyosarcoma, finding no significant additive or synergistic effects and potential antagonistic effects on chemotherapy efficacy.
bioRxiv · May 28, 2019 · PreprintCancer Biology