Origin and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages.
C. C. Bain, D. A. Gibson, N. J. Steers, K. Boufea, P. A. Louwe, C. Doherty, V. Huici, R. Gentek, M. Magalhaes-Pinto, M. Bajenoff, C. Benezech, D. Dockrell, P. T. Saunders, N. Batadar, S. J. Jenkins
This study shows that sex and age influence peritoneal macrophage behavior through bone marrow replenishment and microenvironment signals, affecting disease resistance.
bioRxiv · Nov 14, 2019Immunology