Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein
T. Lukash, T. Agback, F. Dominguez, N. Shiliaev, C. Meshram, E. Frolova, P. Agback, I. Frolov
This study identifies FHL1 as a host factor interacting with CHIKV nsP3 HVD, showing it stimulates replication but is not essential, and highlights additive pro-viral effects with CD2AP.
bioRxiv · Sep 29, 2020Microbiology