Pharmacology & ToxicologybioRxiv
Stimulation of platelet P2Y1 receptors by differentendogenous nucleotides leads to functional selectivity via biased signalling.
K. L. Arkless, D. Pan, M. Shankar-Hari…·S. C. Pitchford
This study shows that different endogenous nucleotides activate P2Y1 receptors with functional selectivity, leading to distinct platelet responses in inflammation versus haemostasis.
DOI 10.1111/bph.16039