Folding heterogeneity in the essential human telomerase RNA three-way junction
C. Palka, N. M. Forino, J. Henstchel, R. Das, M. D. Stone
This study investigates the structural dynamics of the human telomerase RNA three-way junction, revealing that it adopts a heterogeneous ensemble of conformations and that a stable 3WJ is necessary but not sufficient for RNP assembly.
bioRxiv · Dec 14, 2019Biochemistry