Transcriptomic mapping of the inter-individual variability of cellular stress response activation in primary human hepatocytes
M. Niemeijer, W. Wiecek, S. Huppelschoten, P. Bouwman, A. Baze, C. Parmentier, L. Richert, R. S. Paules, F. Y. Bois, B. van de Water
The paper maps inter-individual variability in stress response activation in primary human hepatocytes using transcriptome analysis and population modeling to improve DILI prediction.
bioRxiv · Aug 26, 2021 · PreprintPharmacology & Toxicology