Author

C. R. Hackley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein design· 1

Activity by Year

2020-2020 · peak 1/yr

1 paper

Recent·Most cited

Cas9-HRs: Novel Cas9 Fusion proteins which bypass the rate limiting step of HR repair

C. R. Hackley

This study introduces Cas9-HR fusion proteins that enhance homology-directed repair (HDR) rates and reduce toxicity in mammalian cells by bypassing the rate-limiting step of HR repair.

bioRxiv · May 17, 2020Bioengineering