Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved Fluorescence Correlation Spectroscopy
M. Barbiero, L. Cirillo, S. Veerapathiran, C. Coates, C. Ruffilli, J. Pines
The paper uses FCS and FCCS to study Cyclin B1-Cdk1 interactions in living cells, revealing cell cycle-dependent binding dynamics and a previously unknown unbound pool of Cyclin B1.
bioRxiv · Feb 22, 2022Cell Biology