Author

C. Souque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

C. MacLean· 2 shared J. A. Escudero· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersEvolutionary Biology

C. MacLean

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2 papers

Recent·Most cited

Off-target integron activity leads to rapid plasmid compensatory evolution in response to antibiotic selection pressure

C. Souque, J. A. Escudero, C. MacLean

The paper shows integron activity can drive plasmid evolution by causing off-target inversions that improve plasmid stability and fitness under antibiotic pressure.

bioRxiv · Apr 29, 2022Evolutionary Biology

Integron activity accelerates the evolution of antibiotic resistance

C. Souque, J. A. Escudero, C. MacLean

This study shows that integron activity speeds up antibiotic resistance evolution in P. aeruginosa by enhancing cassette expression and removing redundant elements without harmful side effects.

bioRxiv · Aug 7, 2020Microbiology