An optogenetic approach to control and monitor inflammasome activation.
J. Nadjar, S. Monnier, E. Bastien, A.-L. Huber, C. Oddou, L. Bardoulet, G. Ichim, B. Py, C. Vanbelle, O. Destaing, V. Petrilli
This paper introduces an optogenetic method to control ASC oligomerization, enabling the study of inflammasome activation without PAMPs or DAMPs.
bioRxiv · Jul 25, 2023Immunology