Author

Capucine Siberchicot

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anna CampalansiD· 2 shared Anne Marie Di GuilmiiD· 1 shared Catherine ChailleuxiD· 1 shared Céline Reyes· 1 shared Chantal DesmazeiD· 1 shared Didier TroucheiD· 1 shared Emma Lehir· 1 shared Gueorgui KratassioukiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Anna CampalansORCID

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2 papers

Recent·Most cited

Direct effects on gene transcription revealed by global and CRISPR-targeted oxidative DNA damage

Luana Cintori, Catherine Chailleux, Pauline Maller, Anne Marie Di Guilmi, Capucine Siberchicot, Tomas Caetano, Emma Lehir, Virginie Jouffret, Céline Reyes, Marion Aguirrebengoa, Anna Campalans, Valérie Bergoglio, Didier Trouche, Yvan Canitrot

The paper shows oxidative DNA damage directly affects gene transcription through repair-dependent mechanisms using RNA-Seq, ChIP-seq, and chemogenetic approaches.

bioRxiv · Oct 27, 2026 · PreprintGenomics

G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation.

Sabine Tricot, Capucine Siberchicot, Isaline Bontemps, Chantal Desmaze, Gueorgui Kratassiouk, Marie Vandamme, Guillaume Pinna, Ivan Nemazanyy, Juan Pablo Radicella, Guy Lenaers, Xavier Renaudin, Jérome Lebeau, Anna Campalans

This study shows that the G-quadruplex ligand RHPS4 reduces radioresistance by inhibiting mitochondrial adaptations caused by ionising irradiation.

NAR Cancer · Sep 11, 2025Peer-reviewedCell Biology