Marine sulfated glycans inhibit the binding of Borrelia burgdorferi adhesins to heparin/GAGs
Changkai Bu, Ke Xia, Carly Fernandes, Yi‐Pin Lin, Nikhat Parveen, Vitor Hugo Pomin, Jonathan S. Dordick, Lianli Chi, Fuming Zhang
The paper identifies marine sulfated glycans that inhibit Borrelia burgdorferi adhesins' binding to heparin/GAGs, with specific inhibitors showing varying potency against different adhesins.
bioRxiv · Sep 23, 2026 · PreprintBiochemistry