Author

Carolin Hoefner

ETH ZurichPrimary ORCID profile (0000-0002-4180-2144 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Carolin HoefneriD2 papers · University of Copenhagen

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Maurizio MolinariiD· 2 shared Carmela Galli· 1 shared Concetta GuerraiD· 1 shared Ilaria FregnoiD· 1 shared Tatiana SoldàiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersCell Biology

Maurizio MolinariORCID

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2 papers

Recent·Most cited

The role of N-glycans and their processing in ER-to-lysosome-associated degradation of disease-causing mutant Neuroserpin

Carolin Hoefner, Ilaria Fregno, Maurizio Molinari

This study shows that the Neuroserpin Portland variant is cleared via ERLAD, dependent on persistent glucosylation and specific proteins like Calnexin and FAM134B.

Autophagy Reports · Aug 6, 2026Peer-reviewedCell Biology

TMX5/TXNDC15, a natural trapping mutant of the PDI family is a client of the proteostatic factor ERp44

Tatiana Soldà, Carmela Galli, Concetta Guerra, Carolin Hoefner, Maurizio Molinari

The paper identifies TMX5 as a PDI family member that interacts with ERp44 via disulfide bonds, controlling its ER retention and distribution.

Life Science Alliance · Sep 30, 2024Peer-reviewedCell Biology