Protein co-scientist aided simulations of the structural and functional impact of O-GlcNAc Transferase TPR domain deletions and amino acid substitutions associated with X-Linked Intellectual Disability
Sonja Barth, Allison Bechard, Amelia Kraft, Chakkai Yip, Caleb Aboagye, Charlie Fehl, Geoffrey Siwo
The paper uses computational methods to model structural and functional impacts of TPR domain deletions and amino acid substitutions in OGT linked to X-Linked Intellectual Disability.
bioRxiv · Oct 30, 2026 · PreprintBioinformatics