Distinct roles of Hsp110 proteins in regulating prion propagation
Matteo Mosca, Mariam Ansari, Cristóbal Marrero-Winkens, Charu Sankaran, Basant Abdulrahman, Hermann M. Schätzl
This study investigates the distinct roles of Hsp110 proteins in mammalian prion propagation using CRISPR knockouts and shows varying effects on PrPSc accumulation and seeding activity.
bioRxiv · Oct 16, 2026 · PreprintMolecular Biology