5-Hydroxymethylcytosines from Circulating Cell-free DNA as Diagnostic and Prognostic Markers for Hepatocellular Carcinoma
Jiabin Cai, Lei Chen, Zhou Zhang, Xinyu Zhang, Xingyu Lu, Weiwei Liu, Guoming Shi, Yang Ge, Pingting Gao, Yuan Yang, Aiwu Ke, Linlin Xiao, Ruizhao Dong, Yanjing Zhu, Xuan Yang, , Jia Fan
This study develops a 5-hydroxymethylcytosine (5hmC) diagnostic model from circulating cell-free DNA to detect hepatocellular carcinoma with high accuracy and prognostic value.
bioRxiv · Sep 23, 2018 · PreprintCancer Biology