Author

Chris Weekes

MRC London Institute of Medical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex MontoyaiD· 1 shared Audrey MossleriD· 1 shared Christian SpeckiD· 1 shared Helle D. UlrichiD· 1 shared Korbinian LiebliD· 1 shared L. ReuteriD· 1 shared Lia WillerdingiD· 1 shared Martin ZachariasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alex MontoyaORCID

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1 paper

Recent·Most cited

Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution

Chris Weekes, Lia Willerding, Sanjay P. Khadayate, Korbinian Liebl, Audrey Mossler, Alex Montoya, Vanessa Rauthe, Mohammad Mahdi Karimi, Martin Zacharias, Helle D. Ulrich, Christian Speck, L. Reuter

The paper identifies a DNA-bound intermediate during MCM2-7 helicase activation and shows how DNA unwinding is coupled to helicase complex disassembly and DNA exit.

Nature Communications · Jul 23, 2026Peer-reviewedMolecular Biology