Christopher Williams

Multi-site Assessment of Methods for Cell Preservation Upstream of Single Cell RNA Sequencing

This study evaluates three cell preservation methods for scRNA-seq across multiple sites, showing concordant cell type results but platform-specific gene expression differences and better granulocyte retention with preservation methods.

Reconfiguration of the visual code and retinal cell type complement in closely related diurnal and nocturnal mice

The paper compares retinal cell composition and visual coding between diurnal and nocturnal mice to show how evolutionary changes in cell types reconfigure visual information processing.

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics

The paper uses single-cell genomics to identify shared and disease-specific cell states and gene regulatory networks in three dementias, revealing distinct neuroimmune mechanisms and potential therapeutic targets.