Statistics of Cellular Evolution in Leukemia: Allelic Variations in Patient Trajectories Based on Immune Repertoire Sequencing
Hong Gao, Chunlin Wang, Junhee Seok, Marcus W. Feldman, Wenzhong Xiao
This study develops a statistical model to analyze immune repertoire evolution in CLL patients, identifying relapse risk through deviations from a null model using V-D-J sequencing data.
bioRxiv · Jan 25, 2016 · PreprintEvolutionary Biology