MICRO-TAG enzyme complementation enables quantification of cellular drug-target engagement in temperature series
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery M. Sampson, Daniel T. Starczynowski, Elmar Nurmemmedov
The paper introduces a fluorescence-based method to quantify drug-target engagement in temperature series using split-RNase S complementation.
SLAS DISCOVERY · Nov 22, 2025Peer-reviewedBiochemistry