Pharmacology & ToxicologyCellPeer-reviewed
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Zhengyuan Pang, Verina H. Leung, Cailynn C. Wang…·Ye Li
This paper develops vCATCH to map covalent drug targets across the entire mouse body, revealing new tissue and cell type engagements for afatinib and ibrutinib.