A single epigenetic repressor controls opposing developmental tempos in human neural and cranial neural crest lineages
Zeynep Eda Atmaca Duran, Marcella Birtele, Shweta Mendiratta, Ramesh Yelagandula, Claire Stevens, Suhn K. Rhie, Giorgia Quadrato, Oliver Bell
This study identifies ZNF462 as an epigenetic repressor that controls opposing developmental tempos in human neural and cranial neural crest lineages by regulating lineage-specific enhancers.
bioRxiv · Oct 13, 2026 · PreprintDevelopmental Biology