Author

Connor Douglas

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 3 Neuroscience· 1

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Geneviève KonopkaiD· 4 shared Stefano BertoiD· 3 shared Ashwinikumar KulkarniiD· 2 shared Carol A. TammingaiD· 2 shared Hyeonsoo JeongiD· 2 shared Iksoo HuhiD· 2 shared Isabel MendizabaliD· 2 shared Kazuya ToriumiiD· 2 shared

Activity by Year

2019-2023 · peak 2/yr

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10 top collaborators · 35 mutual co-author links

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4 shared papersGenomics

Geneviève KonopkaORCID

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4 papers

Recent·Most cited

An extra-circadian function for human CLOCK in the neocortex

Yuxiang Liu, Miles R. Fontenot, Ashwinikumar Kulkarni, Nitin Khandelwal, Seon-Hye E. Park, Connor Douglas, Matthew J. Harper, Pin Xu, Nisha Gupta, Jay R. Gibson, Joseph S. Takahashi, Geneviève Konopka

This study shows that human CLOCK has extra-circadian functions in the neocortex, enhancing cognitive flexibility and neural connectivity through altered gene expression in excitatory neurons.

bioRxiv · Mar 13, 2023 · PreprintNeuroscience

Cell-type and cytosine context-specific evolution of DNA methylation in the human brain

Hyeonsoo Jeong, Isabel Mendizabal, Stefano Berto, Paramita Chatterjee, Thomas S. Layman, Noriyoshi Usui, Kazuya Toriumi, Connor Douglas, Devika Singh, Iksoo Huh, Todd M. Preuss, Geneviève Konopka, Soojin V. Yi

The paper investigates DNA methylation evolution in human brain cells, showing reduced CG methylation and increased CH methylation, linked to schizophrenia risk.

bioRxiv · Jul 14, 2020 · PreprintGenomics

The genomic underpinnings of oscillatory biomarkers supporting successful memory encoding in humans

Stefano Berto, Miles R. Fontenot, Sarah E. Seger, Fatma Ayhan, Emre Caglayan, Ashwinikumar Kulkarni, Connor Douglas, Carol A. Tamminga, Bradley Charles Lega, Geneviève Konopka

This paper links brain oscillations to gene expression in human patients, identifying gene modules associated with memory encoding and neuropsychiatric disorders.

bioRxiv · Nov 25, 2019 · PreprintGenomics

Cell-type specific epigenetic links to schizophrenia risk in brain

Isabel Mendizabal, Stefano Berto, Noriyoshi Usui, Kazuya Toriumi, Paramita Chatterjee, Connor Douglas, Iksoo Huh, Hyeonsoo Jeong, Thomas S. Layman, Carol A. Tamminga, Todd M. Preuss, Geneviève Konopka, Soojin V. Yi

The paper analyzes cell-type specific DNA methylation and transcriptomes in schizophrenia brains, finding reduced epigenetic distinction between cell types in schizophrenia.

Genome biology · Jul 9, 2019Peer-reviewedGenomics