Bacterial-derived cyclic lipopeptides suppress dauer arrest in C. elegans
Xiao Wang, Kelsie M. Nauta, Marco E. Mechan Llontop, Darrick R. Gates, Nirmal Chaudhary, Amudha Ramchandran, Kersten K Sykes, Corrie L Sakowski, Vashnie H Hartwell, Jade Tarango, Ashootosh Tripathi, Nicholas O. Burton
This study identifies Massetolide F, a bacterial cyclic lipopeptide, as a molecule that suppresses dauer arrest in C. elegans by inducing acid sphingomyelinase expression.
bioRxiv · Sep 17, 2026 · PreprintMicrobiology