Author

Costis Daskalakis

MIT Computer Science and Artificial Intelligence Laboratory

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Bioengineering· 1

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adam R. KlivansiD· 1 shared Daniel J. DiaziD· 1 shared Giannis Daras· 1 shared Jeffrey Ouyang-ZhangiD· 1 shared Krithika RavishankariD· 1 shared Qiang LiuiD· 1 shared William Daspit· 1 shared

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2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Adam R. KlivansORCID

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1 paper

Recent·Most cited

Ambient Proteins: Training Diffusion Models on Low Quality Structures

Giannis Daras, Jeffrey Ouyang-Zhang, Krithika Ravishankar, William Daspit, Costis Daskalakis, Qiang Liu, Adam R. Klivans, Daniel J. Diaz

Treating low-confidence AlphaFold structures as noisy data at pLDDT-dependent diffusion times lets a 16.7M-parameter model generate long proteins with higher diversity, designability and novelty than Proteína.

bioRxiv · Jul 3, 2025 · PreprintBioengineering✦ In-depth digest