TailEnrich enables discovery of dysregulated genes through disease sample enrichment testing
Hongdong Li, Yuhe Liu, Cuixiang Lin, Shixian Wang, Hui Pan, Shaokai Wang
TailEnrich identifies dysregulated genes in patient subsets by testing expression distribution tails, outperforming DESeq2 and edgeR in simulated data and uncovering novel genes in Alzheimer's disease.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics