N-terminal BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands
M. Day, M. Rappas, K. Ptasinska, D. Boos, A. Oliver, L. Pearl
The paper defines the specificity of N-terminal BRCT domains in TOPBP1/Rad4 for phosphopeptide ligands through structural and biochemical analysis of their interactions with various proteins.
bioRxiv · Jul 13, 2018Biochemistry