STAM Interaction with Hrs Controls JAK/STAT Activation by Interferon-α at the Early Endosome
N. Zanin, C. M. Blouin, C. Viaris de Lesegno, D. Chmiest, L. Johannes, C. Lamaze
This study identifies STAM interaction with Hrs as critical for IFN-α-induced JAK/STAT activation at the early endosome, revealing endosomal sorting's role in differential signaling.
bioRxiv · Jan 2, 2019 · PreprintCell Biology