Author

D. E. Ayer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

B. R. Wilde· 2 shared Z. Ye· 2 shared A. Franzini· 1 shared A. N. Van Scoyk· 1 shared A. Pomicter· 1 shared J. Gertz· 1 shared J. M. Vahrenkamp· 1 shared K. E. Murphy· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

B. R. Wilde

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bioluminescence Assay of Lysine Deacylase Sirtuin Activity

A. N. Van Scoyk, O. Antelope, A. Franzini, D. E. Ayer, R. T. Peterson, A. Pomicter, S. C. Owen, M. W. Deininger

The paper develops SIRTify, a bioluminescence assay to measure sirtuin activity by detecting lysine deacylation, showing it accurately reflects sirtuin specificity and modulator effects.

bioRxiv · Aug 10, 2023Bioengineering

TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding

T.-Y. Lim, B. R. Wilde, M. L. Thomas, K. E. Murphy, J. M. Vahrenkamp, M. E. Conway, K. E. Varley, J. Gertz, D. E. Ayer

This study shows that TXNIP loss increases Myc genomic binding, expanding Myc-dependent transcriptional programs without increasing Myc levels or activity.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production

D. E. Ayer, B. R. Wilde, Z. Ye

The paper shows acidosis activates MondoA by increasing mitochondrial ATP production, which leads to G6P synthesis and nuclear MondoA translocation.

bioRxiv · Jul 24, 2018Cancer Biology

Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation

D. E. Ayer, Z. Ye

This study shows Ras suppresses TXNIP translation by slowing ribosome translocation, despite increasing overall protein synthesis.

bioRxiv · Apr 11, 2018Cancer Biology