Author

D. J. Trader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

A. H. Mahmoud· 1 shared B. L. Zerfas· 1 shared C. Loy· 1 shared E. M. Ali· 1 shared K. L. Mores· 1 shared M. A. Lill· 1 shared R. J. Cassell· 1 shared R. M. van Rijn· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. H. Mahmoud

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2 papers

Recent·Most cited

ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation

E. M. Ali, C. Loy, D. J. Trader

This paper introduces ByeTACs, bifunctional degraders that target proteins by interacting with the 26S proteasome instead of an E3 ligase, and shows they effectively degrade BRD4.

bioRxiv · Jan 20, 2024Biochemistry

Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides

R. J. Cassell, K. L. Mores, B. L. Zerfas, A. H. Mahmoud, M. A. Lill, D. J. Trader, R. M. van Rijn

The paper identifies naturally occurring rubiscolin peptides that selectively activate G-protein signaling at delta opioid receptors with minimal beta-arrestin recruitment.

bioRxiv · Oct 5, 2018Pharmacology & Toxicology